Please, for the love of gravy, do not rely on that little plastic pop-up thing. That thing is a liar. It pops when the turkey is already overdone. You deserve better.
Use an instant-read thermometer. Stick it into the thickest part of the thigh—not touching the bone, that’s cheating. It should read 165°F. Also check the breast: 160°F is fine because it will keep cooking as it rests. The breast is the diva; it dries out fast.
And here’s the most important step: let it rest. For at least 30 minutes. Tented with foil. If you cut into it right away, all those juices will run out onto the cutting board, and your turkey will be as dry as a lecture on tax law. Don’t do that to yourself.
How Long Does It Take to Cook a 20lb Turkey at 350 Degrees
What about stuffing? Oh, you sweet summer child
If you’re stuffing the bird (brave choice), you have to add time. The stuffing needs to hit 165°F too, and it takes forever for the heat to reach the center of a 20-pound bird. We’re talking closer to 5 hours total.
Honestly? Cook your stuffing separately. It’s faster, safer, and you get those crispy edges. The turkey and stuffing can still be friends on the plate. They don’t have to be roommates.