So, does homemade caramel need to be refrigerated? The short answer is, it depends on the type of caramel you're making. If you're making a dry caramel, which is cooked to a higher temperature, it's usually safe to store at room temperature. But, if you're making a wet caramel, which has a higher moisture content, it's best to refrigerate it to prevent bacterial growth.
Now, I know what you're thinking - what's the big deal about refrigeration? Well, my friend, it's all about food safety. You see, bacteria can grow rapidly in caramel that's not stored properly, which can lead to some pretty nasty consequences. So, it's always better to err on the side of caution and refrigerate that caramel!